Barrier-Free Manufacturing
Membio's 0.2-10 L benchtop bioreactor system was built for cost-efficient cell manufacturing.
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Heated Enclosure
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Perfusion Media Bag Hanger
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Rotating Bioreactor Stand
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Peristatic Pump (circulates media between perfusion media bag and bioreactor)
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Enclosure Heater and Circulation Fan
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Touch Screen HMI
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Extendable Bag Hangers
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Peristatic Pumps
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Bioreactor Mounted on Rotating Stand (bioreactor is inverted to mix contents within vessel chamber)
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Refrigerated Compartment (contains stacked bag trays)
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Sliding Bag Hangers
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Compressed Gas Inlets (located on back of system)
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Heated Enclosure
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Perfusion Media Bag Hanger
-
Rotating Bioreactor Stand
-
Peristatic Pump (circulates media between perfusion media bag and bioreactor)
-
Enclosure Heater and Circulation Fan
-
Touch Screen HMI
-
Extendable Bag Hangers
-
Peristatic Pumps
-
Bioreactor Mounted on Rotating Stand (bioreactor is inverted to mix contents within vessel chamber)
-
Refrigerated Compartment (contains stacked bag trays)
-
Sliding Bag Hangers
-
Compressed Gas Inlets (located on back of system)
SMALL FOOTPRINT, LARGE IMPACT
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Gas Perfusion Inlet/Outlet
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Gas Perfusion Membranes
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Sensor Port (ex. O2, pH, temp)
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Vessel Chamber (where cells grow)
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Fluid Management Port
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Liquid Perfusion Membranes
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Liquid Perfusion Inlet/Outlet
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Our Approach to Biomanufacturing
Membio's single-use perfusion bioreactor vessel is designed to scale with flexibility from 0.2-10 L.
Closed Processing
Our bioreactors come with a fully closed single-use fluidics system that can be adapted to the needs of a wide range of processes.
HIGH FLEXIBILITY, LOW RISK
Designed to Maximize Efficiency
Capillaries distributed throughout the human body ensure that cells are never out of reach of the nutrients they need to grow, making it the most efficient nutrient delivery system.
So, we decided to recreate it:
Leveraging Nature's Design
Our bioreactors have gas and liquid perfusion systems that are precisely distributed throughout the vessel chamber so that, just like in the human body, cells are never out of reach of the critical gas and liquid nutrients they need to grow.
MIMICKING THE PERFECT DESIGN
Effortless Scaling from 0.2-10 L
Our system is designed to scale up while maintaining a constant environment.
DESIGNED TO SCALE UP, NOT OUT
Bringing Simplicity to a Complex Process
Membio’s 0.2-10 L system can automate and replace the entire seed train for production volumes to 2,500-L. We achieve high cell densities in our bioreactor using perfusion. This allows us to eliminate intermediary steps and produce enough cells to inoculate bioreactors that are up to 250x as large.
FROM 7 STEPS:
TO 2 STEPS:
Our 10-L bioreactor can seed up to a 2,500-L production bioreactor
SIMPLIFYING BIOMANUFACTURING